Coupling mitochondrial and cell division
نویسندگان
چکیده
منابع مشابه
Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division
During animal cell division, an actin-based ring cleaves the cell into two. Problems with this process can cause chromosome missegregation and defects in cytoplasmic inheritance and the partitioning of organelles, which in turn are associated with human diseases. Although much is known about how chromosome segregation is coupled to cell division, the way organelles coordinate their inheritance ...
متن کاملCoupling cellular oscillators--circadian and cell division cycles in cyanobacteria.
Understanding how different cellular subsystems are coupled to each other is a fundamental question in the quest for reliably predicting the dynamic state of a cell. Coupling of oscillatory subsystems is especially interesting as dynamic interactions play an important role in cell physiology. Here we review recent efforts that investigate and quantify the coupling between the circadian and cell...
متن کاملRegulatory modules: Coupling protein stability to phopshoregulation during cell division.
Multiple post-translational regulation systems regulate cell biology. Two key mechanisms that coordinate the myriad processes of cell replication are phosphorylation and ubiquitin-mediated degradation of proteins. Regulatory modules have evolved to integrate these two control systems at key decision points in the cell division cycle. These modules enable information to be processed with high fi...
متن کاملInhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell.
Mitochondrial dysfunction is an early pathological feature of Alzheimer's disease (AD). The underlying mechanisms and strategies to repair it remain unclear. Here, we demonstrate for the first time the direct consequences and potential mechanisms of mitochondrial functional defects associated with abnormal mitochondrial dynamics in AD. Using cytoplasmic hybrid (cybrid) neurons with incorporated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Cell Biology
سال: 2011
ISSN: 1465-7392,1476-4679
DOI: 10.1038/ncb2334